Pituitary stalk interruption syndrome (PSIS) presenting in a Jordanian male patient with short stature and delayed puberty: a case report

Abstract Background Pituitary stalk interruption syndrome is a rare congenital pituitary anatomical defect manifested with wide and various clinical presentations. Short stature delayed puberty are present in most cases may be combined extra malformations. Magnetic resonance imaging considered the key factor for reaching definite diagnosis as it reveals different radiological presentations of this syndrome. Case presentation A 17-year-old male patient from Jordan was presented to radiology department MRI. The presents multiple hormonal deficiency, short stature, under-developed secondary sexual characteristics. bone age significantly less than chronological age. MRI gland showed hypoplasia anterior pituitary, absence ectopic posterior located optic chiasm. These findings were consistent Conclusions Considering uncommon incidence syndrome, magnetic should while examining deficiency prompt treatment. Hormone replacement medication primary treatment started soon feasible. Thus, early monitoring individuals crucial.